Overactive Bladder Treatments

Following are available treatments at Tower Urology for Overactive Bladder

1. Botox

Botox

BOTOX® (onabotulinumtoxinA) for injection is indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency, in adults who have an inadequate response to or are intolerant of an anticholinergic medication.

BOTOX® is a different type of treatment option to consider when another type of medication (anticholinergic) does not work well enough or cannot be taken.

• BOTOX® is injected into the bladder muscle:
− targeting the source of your Overactive Bladder.
− beginning to reduce daily leakage episodes after just 2 weeks.

• One BOTOX® treatment for OAB can last up to 6 months. Talk to your doctor about your re-treatment timing, waiting at least 3 months between treatments.

• In clinical trials, at week 12, adults using BOTOX® reduced their average number of daily leakage episodes by about half.

Ask your Urologist or Urogynecologist if BOTOX® can help Calm Your Bladder
to significantly reduce your daily leakage episodes.

BOTOX® treatment works by calming the nerves that trigger the overactive bladder muscle.

In your body, certain chemicals travel from nerve cells to muscle cells to make your bladder contract so that you can urinate. With OAB, these muscles contract uncontrollably, creating leakage, the strong sudden need to go, and going too often. BOTOX® is injected into the bladder muscle and works on the nerves to help block the signals that trigger OAB, which helps:

• Reduce daily leakage episodes.

• Treat the strong need to urinate right away.

• Reduce the number of times that you need to empty your bladder daily.

BOTOX® is injected into the bladder muscle and begins to work at the source of your Overactive Bladder to reduce daily leakage episodes after just 2 weeks.
BOTOX® is not a daily treatment. In clinical trials, one BOTOX® treatment provided up to 6 months of OAB symptom improvement. (Your results may vary.)

Talk to your doctor about your re-treatment timing, waiting at least 3 months between treatments.

Patients receiving BOTOX® reported a significant reduction in the number of their daily leakage episodes.

At week 12, many of these patients saw their daily leakage episodes reduced by half or more following BOTOX® treatment.*

  • The majority of patients receiving BOTOX® had at least 50% reduction of daily leakage episodes.
  • Most of these patients reduced their leakage episodes by 75%.
  • Approximately 1 in 4 of them reported they were experiencing no leakage episodes.

In clinical trials, one BOTOX® treatment provided symptom improvement for up to 6 months. Your doctor will work with you to develop a re-treatment plan.

By significantly reducing daily leakage episodes, BOTOX® treatment may make a positive impact on your daily life.

Based on results of a questionnaire* completed by patients in the BOTOX® clinical trials, patients on BOTOX® reported improvement in their overall quality of life. This questionnaire asked patients to consider three specific categories that are commonly important to people living with Overactive Bladder:

  • Avoidance and Limiting Behavior Such as overplanning every detail of your day in advance. Including worrying about where bathrooms are and/or limiting how much fluid you drink.
  • Psychosocial Impact Such as being preoccupied or frustrated with how your condition impacts your everyday decisions, such as what you can wear, where you can go, and how you feel about your overall well-being.
  • Social Embarrassment Such as being embarrassed or worried that your symptoms might be noticed by others.
BOTOX® treatment can be given in the convenience of a doctor’s office.

Once you and your doctor decide that BOTOX® is right for you, very often it can be administered in your Urologist’s or Urogynecologist’s office.

Before your treatment day:

• Your doctor will prescribe an antibiotic to prevent against a urinary tract infection.

On the treatment day:

• Your doctor will numb your bladder for a more comfortable treatment.

• Once your bladder is numb, a small lighted tube called a cystoscope will be inserted through the urethra (the natural opening where the urine comes out).

• BOTOX® is injected through the cystoscope into multiple areas of your bladder muscle.

• The entire process takes approximately one hour: 30 minutes to prepare and administer the BOTOX® and 30 minutes for post-procedure evaluation.

2. Urgent PC

Non-drug, Non-surgical Treatment for Overactive Bladder

What is Urgent PC?

Since 2003, healthcare professionals have used the Urgent PC Neuromodulation System to treat overactive bladder and associated symptoms of urinary urgency, urinary frequency and urge incontinence. Talk to your clinician to learn more about these symptoms.

The Urgent PC Neuromodulation System is a combination of a hand-held stimulator, thin needle electrode and a lead set. The stimulator generates electrical impulses that are delivered to the patient through the lead set.

The Urgent PC system delivers a specific type of neuromodulation called percutaneous tibial nerve stimulation (PTNS). During treatment, a small, slim needle electrode is inserted near your ankle. The needle electrode is then connected to the battery-powered stimulator. During your 30-minute treatment, mild impulses from the stimulator travel through the needle electrode, along your leg and to the nerves in your pelvis that control bladder function. This process is also referred to as neuromodulation.
Because patients may experience the sensation of the Urgent PC therapy in different ways, it’s difficult to say what the treatment would feel like to you. Patients often describe the sensation as “tingling,” or “pulsating.” Treatment is typically well-tolerated by patients. Urgent PC offers many different levels of stimulation, so your clinician will be able to adjust treatment to suit you as well as address any discomfort that you might experience during treatment.
You will receive an initial series of 12 treatments scheduled about a week apart. After the initial 12 treatments, your physician will work with you to determine if occasional treatments are needed to maintain your results. The time between follow-up treatments can range from every few weeks to every few months.
60-80% of patients see a satisfactory improvement in their symptoms. Urgent PC may work, even if other treatments, such as medications, have failed.

Because Urgent PC gently modifies the signals to achieve bladder control, it usually takes 5-7 weeks for symptoms to change. However, patients respond at different rates. In a review of about 100 patients who had success with Urgent PC, symptoms improved anywhere between 2-12 weeks. For about 20% of these patients, the symptoms of urgency and/or urge incontinence didn’t improve until after 8 weeks. 1

There is no way to anticipate who will respond earlier, later or not at all. That’s why it is important to receive the 12 recommended treatments before you and your physician evaluate whether this therapy is an appropriate and effective choice for you.

Urgent PC is an option for patients with OAB. If you think you have OAB, talk to your doctor, a urologist or urogynecologist. If you have OAB, the doctor will work with you to determine your own personal treatment plan which usually starts with behavior and diet modifications plus medications. Urgent PC is an excellent option if these options don’t work or provide sufficient improvements. Treatment with Urgent PC is typically performed at a Urologist, Urogynecologist or Obgyn office. So, if you run out of options with your normal doctor, consider visiting one of these specialists.

Yes, these include: patients with pacemakers or implantable defibrillators, patients prone to excessive bleeding, patients with nerve damage that could impact either percutaneous tibial nerve or pelvic floor function and patients who are pregnant or planning to become pregnant during the duration of the treatment.

The risks associated with Urgent PC therapy are low. Most common side-effects are temporary and include mild pain or skin inflammation at or near the stimulation site.