What is Botox?
Most people likely associate Botox (onabotulinumtoxinA) and its close cousin, Dysport (abobotulinumtoxinA), with cosmetic procedures to temporarily reduce the appearance of wrinkles. It may be less well-known that they are also FDA-approved treatments for various medical conditions, including excessive sweating, overactive bladder, chronic migraines, and muscle stiffness and spasms.
Both are derived from botulinum neurotoxin (or simply botulinum toxin) and are injectable medications used to block nerve signals to muscles, causing them to relax.
More recently, research and randomized clinical trials have investigated the muscle relaxation effects of these substances on erectile dysfunction (ED).

How do Botox and Dysport work for erectile dysfunction?
Scientific studies investigating the effectiveness and tolerability of Botox and Dysport in treating erectile dysfunction (ED) have revealed an impressive response.
Let’s look at the basic mechanics of an erection: the relaxation of the arterial smooth muscles causes them to dilate, which allows for increased blood flow to the penis, leading it to become rigid.
Disruption of nerve signals, loss of smooth muscle control, and reduced blood flow can all contribute to erectile dysfunction (ED).
By blocking nerve signals to the smooth muscles that prevent or reduce relaxation and decrease muscle tone in specific areas, Botox and Dysport have both demonstrated the ability to increase relaxation and, in turn, enhance blood flow to the penis.
The bottom line is that this helps to improve the ability to achieve and maintain erections, leading to stronger erections and improved sexual activity.
How effective are Botox and Dysport for severe erectile dysfunction?
Dysport and Botox for ED are particularly effective for men whose ED is associated with vascular (related to blood flow) or neurogenic (nerve-related) causes.
However, there have also been encouraging results in the treatment of men with severe erectile dysfunction. Overall, men in this difficult-to-treat category demonstrated a 54% response rate after Botox or Dysport administration, which is relatively high.
Interestingly, the rate of success appeared unrelated to the cause of erectile dysfunction (ED). Furthermore, none of the men in this group reported any side effects or worsening of their severe ED.
How long do Botox and Dysport last for erectile dysfunction?
Similar to the effect on facial muscles, the impact of Dysport or Botox treatment for ED is temporary. The effects are gradual, with the full effects felt approximately two weeks later, lasting between three and six months.
To continue to enjoy the effects of this therapy, ongoing treatment is required.
Are Botox and Dysport safe for treating erectile dysfunction?
Yes. While side effects linked to Botox and Dysport for cosmetic purposes include flu-like symptoms, nausea, and headaches, studies have shown that patients treated for ED with Botox or Dysport reported none of the side effects associated with either substance.
Since everyone responds differently to Botox and Dysport, we start with the lowest dosage and, if necessary, increase to a higher dose based on your response.
After injecting the Botox or Dysport, we take steps to ensure that the substance remains in the penis for adequate tissue uptake. This reduces the likelihood of it spreading into the bloodstream and helps avoid potential side effects.
What types of erectile dysfunction does Botox treat?
This procedure is primarily used to treat ED that fall into one of the following categories:
- ED caused by poor blood flow or vascular insufficiency (damaged or weakened veins).
- Neurogenic ED is caused by nerve damage or dysfunction.
- ED in men who have not responded well to traditional treatments such as oral medications.
Who is the ideal candidate for Botox or Dysport for erectile dysfunction?

The ideal candidates for Botox or Dysport therapy for ED include:
- Men with moderate ED who have not achieved satisfactory results from oral medications like Viagra or Cialis.
- Individuals seeking a non-surgical and minimally invasive treatment option to improve their ED symptoms.
- Patients who do not have contraindications for botulinum toxin, such as those with certain neuromuscular conditions.
A consultation with our specialists will help determine if this treatment is proper for you.
How is the procedure performed?
The procedure for treating ED with Botox or Dysport therapy involves the following steps:
- The procedure is performed in an outpatient setting and typically takes 30 minutes.
- A topical anesthetic is applied to minimize discomfort.
- Small doses of the substance are injected into targeted areas of the penile tissue or surrounding muscles.
This minimally invasive approach ensures a comfortable experience without extensive downtime. Our team at Tower Urology ensures you are equipped with all necessary aftercare and follow-up instructions.
What are the risk factors?
Botox and Dysport for ED are generally safe when performed by experienced specialists. Our team prioritizes safety and ensures all procedures are performed precisely and carefully.
Potential risks and side effects include:
- Temporary bruising or swelling at the injection site.
- Mild discomfort during or after the procedure.
- Muscle weakness is caused by the unintended spread of botulinum toxin to adjacent areas, but this is rare.
What is Botox for ED’s recovery like?
Recovery is quick and straightforward. Most patients will:
- Resume normal activities immediately after the procedure.
- Experience minimal to no downtime.
- Notice gradual improvements in erectile function over a few weeks.
Are there other treatment options for erectile dysfunction to consider?
Alternative treatments for ED include:
- Oral medications: PDE5 inhibitors like Viagra or Cialis remain first-line options.
- Platelet-rich plasma (PRP) therapy: PRP injections for regenerative treatment.
- Shockwave therapy: Non-invasive treatment to improve blood flow.
- Penile implants: For severe or refractory cases of ED.
Our specialists will discuss these options with you to determine the best course of action tailored to your specific needs.
Why is Tower Urology the best treatment option for Botox for erectile dysfunction in Los Angeles?
Our commitment to excellence and the advancement of sexual medicine makes Tower Urology a trusted provider of Botox and Dysport for ED and other ED treatments in Los Angeles.
Botox and Dysport for ED are exciting and emerging treatments, but may not be suitable for everyone. We encourage our patients to maintain realistic expectations. This type of therapy is most effective as part of a comprehensive approach to men’s sexual health, which may include lifestyle changes, addressing underlying health conditions, and exploring other treatment options.
At Tower Urology, when you consult with your men’s health physician, we will discuss all options available to you and guide you to make the best decision to help you address your ED symptoms and facilitate improved sexual activity and overall well-being.
You will receive a customized treatment plan tailored to your current erectile function, the treatments you have already tried, and your personal and medical history.
Our team is here to support you every step of the way, ensuring you feel informed and confident about your care.
Tower Urology’s board-certified urologists have been leaders in successfully treating erectile dysfunction (ED) for decades, with specialists trained in all aspects of urological care.
At Tower Urology, we offer:
- Expertise in men’s health: Our specialists are leaders in the field, trained in advanced and innovative treatments for erectile dysfunction (ED).
- State-of-the-art technology: We utilize the latest tools and techniques to ensure safety and efficacy.
- Patient-centered care: Each treatment plan is customized to your health goals and concerns.
Tower Urology’s advantage lies in our unwavering commitment to providing world-class urologic care through advanced technology, personalized treatment plans, and a patient-centered approach. With a reputation for excellence and innovation, we deliver superior outcomes that set us apart as a leader in urologic health.
We invite you to establish a care plan with Tower Urology.
Tower Urology is a proud affiliate of Cedars-Sinai Medical Center, ranked #1 in California and #2 in the nation by U.S. News & World Report. This partnership reflects our commitment to delivering the highest standard of urologic care with the best urologists in Los Angeles. Our years of experience, combined with access to Cedars-Sinai’s world-class facilities, and our exceptional, innovative, and state-of-the-art urological care make Tower Urology a leader in Southern California.
Tower Urology is conveniently located for patients throughout Southern California and the Los Angeles area, Beverly Hills, Santa Monica, West Los Angeles, West Hollywood, Culver City, Hollywood, Venice, Marina del Rey, and Downtown Los Angeles.
Services include treatment for azoospermia, delayed ejaculation, erectile dysfunction, low libido in men, and premature ejaculation.
Sources
An update on emerging drugs for the treatment of erectile dysfunction
https://www.tandfonline.com/doi/abs/10.1080/14728214.2018.1552938
Botox for Erectile Dysfunction
https://academic.oup.com/jsm/article-abstract/14/2/177/6973339
Summary of the Recommendations on Sexual Dysfunctions in Men
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1743-6109.2010.02062.x
Safety and Effectiveness of Repeated Botulinum Toxin A Intracavernosal Injections in Men with Erectile Dysfunction Unresponsive to Approved Pharmacological Treatments: Real-World Observational Data
https://pmc.ncbi.nlm.nih.gov/articles/PMC10301648